Brevets / Publications / Communications
Brevets
• Berti L, Bolla J-M, Brunel J-M, Casanova J, Lorenzi V. « Use of polyaminoisoprenyl derivatives in antibiotic or antiseptic treatment »: Extension PCT déposée le 23/02/2012 (PCT/EP2012/053113). Licensed by Vibiophen (Labège, France) in 2016.
• Franceschi C, Pinet E, Pagès J-M, Zambardi G. « Identification des bactéries résistantes aux carbapénèmes par Imperméabilité membranaire ». 2015.
Déclaration d’invention
• « Novel biocides on the electromodulable phosphonium conducting polymers » (Partenariat CiNaM, UMR_MD1).
Publications
• Fankam AG et al. Antibacterial activities of selected Cameroonian spices and their synergistic effects with antibiotics against multidrug-resistant phenotypes. BMC Complement Altern Med. 2011;11:104.
• Voukeng IK et al. Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypes. BMC Res Notes. 2012;5:299.
• Fadli M et al. Antibacterial activity of Thymus maroccanus and Thymus broussonetii essential oils against nosocomial infection-bacteria and their synergistic potential with antibiotics. Phytomedicine. 2012;19:464.
• Goemaere E et al. New PDF-Inhibitors and cooperative interaction : a combination to improve antibacterial activity. J Antimicrob Agents. 2012;67:1392.
• Lacmata ST et al. Antibacterial Activities of Selected Cameroonian Plants and Their Synergistic Effects with Antibiotics against Bacteria Expressing MDR Phenotypes. Evid Based Complement Alternat Med. 2012;2012:623723.
• Fadli M et al. Thymus maroccanus essential oil, a membranotropic compound active on Gram-negative bacteria and resistant isolates. J Appl Microbiol. 2012;113:1120.
• Lieutaud A et al. Inhibitors of Antibiotic Efflux by AcrAB-TolC in Enterobacter aerogenes. Anti-Infect Agents. 2013;11:168.
• Handzlik J et al. Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin. Bioorg Med Chem. 2013;21:135.
• Brunel J-M et al. Polyamino geranic derivatives as new chemosensitizers to combat antibiotic resistant Gram-negative bacteria. Bioorg Med Chem. 2013;21:1174.
• Fadli M et al. Natural extracts stimulate membrane-associated mechanisms of resistance in Gram-negative bacteria. Lett Appl Microbiol. 2014;58:472.
• Fadli M et al. First evidence of antibacterial and synergistic effects of Thymus riatarum essential oil with conventional antibiotics. Ind Crops Prod. 2014;61:370.
• Pieri C et al. New ianthelliformisamine derivatives as antibiotic enhancers against resistant gram-negative bacteria. J Med Chem. 2014;57:4263.
• Allam A et al. New peptides with metal binding abilities and their use as drug carriers. Bioconjug Chem. 2014;25:1811.
• Philippe N et al. In vivo evolution of bacterial resistance in two cases of Enterobacter aerogenes infections during treatment with imipenem. PLoS ONE. 2015;10(9):e0138828.
• Pagès J-M et al. The role of the outer membrane and porins in the susceptibility of β-lactamase-producing Enterobacteriaceae to ceftazidime-avibactam. Antimicrob Agents Chemother. 2015;60:1349.
• Otrebska-Machaj E et al. Efflux pump blockers in Gram-negative bacteria: new hydantoin based modulators to improve antibiotic activity. Frontiers Microb. 2016;7:622.
• Borselli D et al. Polyamino-isoprenic derivatives block intrinsic resistance of P. aeruginosa to doxycycline and chloramphenicol in vitro. PLoS ONE. 2016;11(5):e0154490.
• Brunel F et al. Antibacterial activities of fluorescent nano assembled triphenylamine phosphonium ionic liquids. Bioorg Med Chem Lett. 2016. pii: S0960-894X(16)30540-6.
• Fadli M et al. Artemisia herba-alba Asso and Cymbopogon citratus (DC.) Stapf essential oils and their capability to restore antibiotics efficacy. Ind Crops Prod. 2016;89:399.
• Fieulaine S et al. A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Reports 6. 2016; ID 35429. doi:10.1038/srep35429.
• Borselli D et al. Motuporamine Derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria. Chem Biochem. 2017;18:276.